Associated with human bacterial vaginosis (nonspecific vaginitis), but role in pathogenicity is not known.
Phylum Actinobacteria, Class Actinobacteria, Subclass Actibacteridae, Order Actynomycetales, Suborder Actinomycinae, Family
Actinomycetaceae, Genus Mobiluncus, Mobiluncus mulieris Spiegel and Roberts 1984 emend. Hoyles, Collins, Falsen, Nikolaitchouk
and McCartney 2004.
Historical synonyms: Falcivibrio grandis Hamman et al. 1984.
Gram-variable curved rods with tapered ends, 2.5-5.0 / 0.4-0.6 µm, occurring singly or
in pairs then S- or U-shape. Non-spore-forming. Motile by multiple subterminal
Colonies are convex, colorless or cream to light-brown (on chocolate agar), smooth,
translucent, 2-4 mm in diameter after 5 days of anaerobic incubation at 37 ºC.
Anaerobic. Grows on BHI (Difco) agar (2%) supplemented with 5% sheep blood and
2% proteose peptone no. 3 (Difco), on brucella agar (Difco) supplemented with 5%
sheep blood and chocolate agar. Grows well in PY broth supplemented with rabbit
serum and glycogen or maltose. CAMP reaction is positive on brucella agar. Grows
at/in: 35-42 ºC, pH 6.0-7.2 and 1% NaCl.
Isolated from human vaginae.
- Spiegel C.A. and Roberts M., 1984. Mobiluncus gen. nov. Mobiluncus curtisii subsp. curtisii sp. nov. Mobiluncus curtisii subsp.
holmesii subsp. nov. , and Mobiluncus mulieris sp. nov., Curved Rods from the Human Vagina. Int J Syst Bact 34 (2) 177-184.
- Hoyles L., Collins M.D., Falsen E., Nikolaitchouk N. and McCartney A., 2004. Transfer of Members of the Genus Falcivibrio to the
Genus Mobiluncus, and Emended Description of the Genus Mobiluncus. System Appl Microbiol 27, 72-83.
Description is based on API ZYM, API CORYNE, API 32AN and RapID 32 Strep results.
Positive results for alpha-glucosidase, leucine arylamidase, starch hydrolysis and acid production from maltose.
Negative results for acid phosphatase, arginine dihydrolase, catalase, cystine arylamidase, esculin hydrolysis, gelatin hydrolysis,
alpha- and beta-galactosidase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-glucosidase, hippurate hydrolysis, H2S
production, indole production, lecithinase, lipase (C14), alpha-mannosidase, serine arylamidase, oxidase, pyrazinamidase, trypsin,
alpha-chymotrypsin, valine arylamidase, acid production from adonitol, amygdalin, cellobiose, cyclodextrin, erythritol, esculin, inulin,
lactose, mannitol, melibiose, raffinose, salicin and sorbitol.
Variable results for alkaline phosphatase, esterase lipase (C8), alpha-fucosidase, nitrate reduction, phosphoamidase, acid
production from L-arabinose, fructose, galactose, D-glucose, glycogen, inositol, mannose, melezitose, ribose, rhamnose, sucrose,
starch, tagatose, trehalose and D-xylose.
(c) Costin Stoica