Associated with human bacterial vaginosis (nonspecific vaginitis), but role in pathogenicity is not known.
Phylum Actinobacteria, Class Actinobacteria, Subclass Actibacteridae, Order Actynomycetales, Suborder Actinomycinae, Family
Actinomycetaceae, Genus Mobiluncus, Mobiluncus curtisii Spiegel and Roberts 1984 emend. Hoyles, Collins, Falsen, Nikolaitchouk
and McCartney 2004.
Historical synonyms: Falcivibrio vaginalis Hammann et al. 1984; Mobiluncus curtisii subsp. curtisii Spiegel and Roberts 1984;
Mobiluncus curtisii subsp holmesii Spiegel and Roberts 1984.
Gram-variable slightly curved rods with tapered ends, 2-3 / 0.4-0.6 µm, occurring
singly or in pairs with a gullwing appearance. Motile by multiple subterminal flagella.
Colonies are convex, colorless or cream to light-brown (on chocolate agar), smooth,
translucent, 2-4 mm in diameter after 5 days of anaerobic incubation at 37 ºC. Grows
on BHI (Difco) agar (2%) supplemented with 5% sheep blood and 2% proteose
peptone no. 3 (Difco), on brucella agar (Difco) supplemented with 5% sheep blood
and chocolate agar. Grows well in PY broth supplemented with rabbit serum and
glycogen or maltose. CAMP reaction is weak (on brucella agar). Grows at 35-42 ºC, at
6.0-7.2 pH and in 1% NaCl. Anaerobic.
Isolated from human vaginae.
- Spiegel C.A. and Roberts M., 1984. Mobiluncus gen. nov. Mobiluncus curtisii subsp. curtisii sp. nov. Mobiluncus curtisii subsp.
holmesii subsp. nov. , and Mobiluncus mulieris sp. nov., Curved Rods from the Human Vagina. Int J Syst Bact 34 (2) 177-184.
- Hoyles L., Collins M.D., Falsen E., Nikolaitchouk N. and McCartney A., 2004. Transfer of Members of the Genus Falcivibrio to the
Genus Mobiluncus, and Emended Description of the Genus Mobiluncus. System Appl Microbiol 27, 72-83.
Description is based on API ZYM, API CORYNE, API 32AN and RapID 32 Strep results.
Positive results for arginine dihydrolase and starch hydrolysis.
Negative results for catalase, cystine arylamidase, alpha-fucosidase, gelatin hydrolysis, beta-glucosidase,
N-acetyl-beta-glucosaminidase, H2S production, indole production, lecithinase, lipase (C14), alpha-mannosidase, oxidase, serine
arylamidase, trypsin, alpha-chymotrypsin, valine arylamidase, acid production from adonitol, amygdalin, L-arabinose, cellobiose,
cyclodextrin, erythritol, esculin, glycogen, inositol, inulin, mannitol, melezitose, rhamnose, ribose, sorbitol, salicin, sucrose, starch,
tagatose and trehalose.
Variable results for acid and alkaline phosphatase, esculin hydrolysis, esterase lipase (C8), alpha- and beta-galactosidase,
alpha-glucosidase, beta-glucuronidase, hippurate hydrolysis, leucine arylamidase, nitrate reduction, phosphoamidase,
pyrazinamidase, acid production from fructose, galactose, D-glucose, lactose, maltose, melibiose, mannose, raffinose and D-xylose.
(c) Costin Stoica