Mycobacterium shinjukuense
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Taxonomy
Morphology
Cultural characteristics
Biochemical characters
Ecology
Pathogenicity
References
Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium shinjukuense Saito et al. 2011.
Acid-alcohol-fast rods.
Colonies on 2% Ogawa egg medium are smooth and non-chromogenic. Growth is
observed following incubation for 21 days at 30-37 ºC; no growth at 25 or 45 ºC. No
growth in 5% NaCl media.
Isolated from sputum and bronchial lavage fluid samples in Japan and Korea.
Susceptible to isoniazide (0.2 / 1 µg/ml), rifampicin (40 µg/ml), ethambutol (2.5 µg/ml), levofloxacin (1 µg/ml), ethionamide (20 µg/ml),
kanamycin (20 µg/ml), cycloserine (30 µg/ml), and streptomycin (10 µg/ml). Resistant to paraaminosalicylic acid (1 µg/ml) and
eniviomycin (2.5 µg/ml).
Undetermined. Associated with lung disease.
- Saito H, Iwamoto T, Ohkusu K, Otsuka Y, Akiyama Y, Sato S, Taguchi O, Sueyasu Y, Kawabe Y, Fujimoto H, et al. Mycobacterium
shinjukuense sp. nov., a slowly growing, non-chromogenic species isolated from human clinical specimens. Int J Syst Evol
Microbiol 2011; 61:1927-1932.
- Watanabe K, Shinkai M, Yamaguchi N, Shinoda M, Hara Y, Ishigatsubo Y, Kaneko T. Mycobacterium shinjukuense lung disease
that was successfully treated with antituberculous drugs. Intern Med. 2013;52(23):2653-5. doi: 10.2169/internalmedicine.52.1116.
PMID: 24292757.
- Seong Mi Moon, Su-Young Kim, Myung Jin Chung, Seung Heon Lee, Sung Jae Shin, Won-Jung Koh. Nontuberculous
Mycobacterial Lung Disease Caused by Mycobacterium shinjukuense: The First Reported Case in Korea Tuberc Respir Dis.
2015;78(4):416-418. Published online October 1, 2015 DOI: https://doi.org/10.4046/trd.2015.78.4.416
- Oshima K, Yokouchi H, Minemura H, Saito J, Tanino Y, Munakata M. Pulmonary infection caused by Mycobacterium shinjukuense.
Ann Am Thorac Soc 2015;12:958-959. PMID: 26075560.
Positive results for thermo-stable catalase (68 ºC), nitrate reductase, pyrazinamidase and Tween 80 hydrolysis.
Negative results for arylsulfatase (3 days), semi-quantitative catalase, and urease.
(c) Costin Stoica