Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium parmense Fanti et al. 2004.
Member of the Mycobacterium simiae complex.
Acid-alcohol-fast, small rods. Does not produce capsules or spores. Non-motile.
Colonies on Lowenstein-Jensen medium after 2 weeks incubation are small (< 1
mm), round, smooth, raised with round or lobate regular margins. Scotochromogenic.
Temperature range for growth is 25-37 ºC; does not grow at 42 ºC or above. Does not
grow on MacConkey agar (without crystal violet) or on 5% (w/v) NaCl agar.
Isolated from a cervical lymph node of a 3-year-old child with bilateral lymphadenitis. Susceptible to ciprofloxacin, clofazimine,
hydroxylamine (500 μg/ml), ethambutol (2 μg/ml), rifampin (32 μg/ml), and streptomycin (8 μg/ml). Resistant to isoniazid (1 μg/ml),
and thiophene-2-carboxylic acid hydrazide.
Has been identified as the cause of cervical lymphadenitis in a child.
- John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
- Fanti F, Tortoli E, Hall L, Roberts GD, Kroppenstedt RM, Dodi I, Conti S, Polonelli L, Chezzi C. Mycobacterium parmense sp. nov.
Int J Syst Evol Microbiol 2004; 54:1123-1127.
Positive results for heat-stable catalase (68 ºC), Tween 80 hydrolysis, and urease.
Negative results for arylsulfatase (3 days), semiquantitative catalase test, beta-glucosidase, niacin accumulation, nitrate reduction, and
tellurite reduction (9 days).
(c) Costin Stoica