| Mycobacterium noviomagense |
Taxonomy
Morphology
Cultural characteristics
Biochemical characters
Ecology
Pathogenicity
References
Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium noviomagense van Ingen et al. 2009.
Mycobacterium, Mycobacterium noviomagense van Ingen et al. 2009.
Acid-fast rods. Gram-positive.
Colonies are nonchromogenic and appear after 4 weeks of culture at 37 ºC, no
growth occurs at 45 ºC. No growth in 5% NaCl.
growth occurs at 45 ºC. No growth in 5% NaCl.
Isolated from sputum, broncho-alveolar lavage fluid and from a post-mortem lung biopsy.
Susceptible to isoniazid (10 μg/ml), streptomycin, cycloserine, prothionamide, amikacin, ciprofloxacin, clofazimine, clarithromycin and
rifabutin. Resistant to thiophene 2-carboxylic acid, para-nitrobenzoate (500 μg/ml), rifampicin (MIC 2 μg/ml). Variable resistance to
hydroxylamine (250 μg/ml), ethambutol (MIC 10-20 μg/ml).
Susceptible to isoniazid (10 μg/ml), streptomycin, cycloserine, prothionamide, amikacin, ciprofloxacin, clofazimine, clarithromycin and
rifabutin. Resistant to thiophene 2-carboxylic acid, para-nitrobenzoate (500 μg/ml), rifampicin (MIC 2 μg/ml). Variable resistance to
hydroxylamine (250 μg/ml), ethambutol (MIC 10-20 μg/ml).
Undetermined.
- van Ingen J, Boeree MJ, de Lange WC, de Haas PE, van der Zanden AG, Mijs W, Rigouts L, Dekhuijzen PN, van Soolingen D.
Mycobacterium noviomagense sp. nov.; clinical relevance evaluated in 17 patients. Int J Syst Evol Microbiol 2009; 59:845-849.
Negative results for acid phosphatase, semi-quantitative catalase, niacin production, nitrate reductase, Tween 80 hydrolysis, and
urease.
urease.
(c) Costin Stoica
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