Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium mucogenicum Springer et al. 1995.
Acid-alcohol-fast, curved rods. Gram-positive. Non-spore-forming.
Colonies are usually smooth, off-white in color, mucoid, and non-pigmented. The
temperature range for growth is 28-37 ºC; does not grow at 42 or 45 ºC. Growth
appears on Middlebrook 7H10 and trypticase soy agars in 2-4 days. Grows on
MacConkey agar without crystal violet (sometimes weakly or not growing) , but not on
agar supplemented with 5% (w/v) NaCl.
Isolated from outbreaks of peritonitis associated with automated peritoneal dialysis machines and water. Susceptible to amikacin,
imipenem, cefoxitin, clarithromycin, and ciprofloxacin. Resistant to isoniazid and rifampin.
Associated with some incidents of post-traumatic wound infection and catheter-related sepsis.
- Springer B, Bottger EC, Kirschner P, Wallace RJJ. Phylogeny of the Mycobacterium chelonae-like organism based on partial
sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int J Syst Bacteriol 1995; 45:262-267.
- John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
- Adekambi T, Berger P, Raoult D, Drancourt M. rpoB gene sequence-based characterization of emerging non-tuberculous
mycobacteria with descriptions of Mycobacterium bolletii sp. nov., Mycobacterium phocaicum sp. nov. and Mycobacterium
aubagnense sp. nov. Int J Syst Evol Microbiol 2006; 56:133-143.
- Gomila M, Ramirez A, Gasco J, Lalucat J. Mycobacterium llatzerense sp. nov., a facultatively autotrophic, hydrogen-oxidizing
bacterium isolated from haemodialysis water. Int J Syst Evol Microbiol 2008; 58:2769-2773.
Positive results for arylsulfatase (3 and 14 days), esculin hydrolysis, pyrazinamidase, tellurite reduction, Tween 80 hydrolysis, and
Can utilize as sole carbon source D-mannitol and citrate (most strains).
Negative results for arginine dihydrolase, catalase (semi-quantitative) (most strains), heat-stable catalase, beta-galactosidase,
alpha-glucosidase, beta-glucuronidase, gelatinase, H2S production, indole production, iron uptake, lysine decarboxylase, ornithine
decarboxylase and tryptophan deaminase.
No utilization of i-myo-inositol and sorbitol as sole carbon sources.
Variable results for nitrate reduction.
(c) Costin Stoica