Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium malmesburyense Gcebe et al. 2017.
Old synonym (not valid): "Mycobacterium malmesburii" Gcebe et al. 2016.
Colonies form a yellow pigment in the dark, and grow on Lowenstein-Jensen slants
supplemented with PACT (polymyxin B, amphotericin B, carbenicillin and
trimethoprim), and on Middlebrook 7H11 at 25, 37 and 45 ºC (optimally at 37 ºC),
within 2-5 days. No growth in 5% (w/v) NaCl.
Isolated from soil, water, nasal swabs and lymph nodes of cattle and pharyngeal swabs of buffalo samples in South Africa.
Resistant to imipenem, tobramycin, cefoxitin and amoxylin. Susceptible to ciprofloxacin, clarithromycin and doxycycline.
- Gcebe N, Rutten V, Pittius NGV, Naicker B, Michel A. Mycobacterium malmesburyense sp. nov., a non-tuberculous species of the
genus Mycobacterium revealed by multiple gene sequence characterization. Int J Syst Evol Microbiol 2017; 67:832-838.
- Gcebe N, Rutten VPMG, van Pittius NG, Naicker B, Michel AL. Mycobacterium komaniense sp. nov., a rapidly growing non-
tuberculous Mycobacterium species detected in South Africa. Int J Syst Evol Microbiol 2018; 68:1526-1532.
- Gcebe N, Rutten V, Gey van Pittius NC, Michel A. Prevalence and distribution of non-tuberculous mycobacteria (NTM) in cattle,
African buffaloes (Syncerus caffer) and their environments in South Africa. Transbound Emerg Dis 2013;60:74-84.
- Gcebe N, Michel A, Gey van Pittius NC, Rutten V. Comparative Genomics and Proteomic Analysis of Four Non-tuberculous
Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins. Front Microbiol
Positive results for semiquantitative catalase test (>45 mm foam), nitrate reductase, pyrazinamidase, Tween 80 hydrolysis, and
Negative results for esculin hydrolysis.
No utilization of citrate, D-mannitol, inositol, L-rhamnose or L-arabinose.
Variable results for arylsulfatase (3 and 14 days) and niacin accumulation.
(c) Costin Stoica