Mycobacterium lepraemurium
Taxonomy
Morphology
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Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium,
Mycobacterium lepraemurium Marchoux and Sorel 1912.
Strongly acid-fast irregular with slightly rounded ends, 3-5 μm in length rods.
Difficult cultivation. Dense compact inocula on Ogawa egg medium leads to the
growth ofrough, non-chromogenic colonies after incubation for 4-5weeks at 30-37 ºC.
Growth also occurs on agar-based media supplemented with cytochrome c and
alpha-ketoglutaric acid. No growth at 42 ºC. No growth on 5%(w/v) NaCl.
Source is unknown. Susceptible to hydroxylamine (500 mg/l).
Pathogenic to rats occuring mainly in the lymph nodes and skin. Produce induration, alopecia, and eventual ulceration.
  1. John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
    Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
  2. Rastogi N, Legrand E, Sola C. The mycobacteria: an introduction to nomenclature and pathogenesis. Rev Sci Tech. 2001;20(1):21‐
    54. doi:10.20506/rst.20.1.1265
Positive results for pyrazinamidase activity (negative in Rastogi's paper).

Negative results for acid phosphatase, arylsulphatase (3, 7 and 10 days), heat-stable catalase, semiquantitative catalase test, nitrate
reduction, niacin production, nicotinamidase, Tween 80 and urea hydrolysis

Variable results for alpha-esterase activity.
(c) Costin Stoica
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