Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium cosmeticum Cooksey et al. 2004.
Acid-fast rods, 0.55 x 1.5 μm. Non-motile. Non-spore-forming. Rarely form cell
aggregates in liquid culture. Cell branching is not present.
Colonies are smooth, domed and scotochromogenic, with a pale yellow coloration on
Lowenstein–Jensen medium and on Middlebrook 7H10 agar. Growth from dilute
inocula appears after 3 days incubation on Löwenstein-Jensen medium at 28-37 ºC;
does not grow at 45 ºC. Grows on MacConkey agar (without crystal violet), but not on
agar supplemented with 5% (w/v) NaCl.
Isolated from from footbath drains and a sink at a nail salon in USA, from a man with pulmonary disease, and from a granulomatous
lesion of a female patient in Venezuela who was undergoing mesotherapy. Susceptible in vitro to ciprofloxacin, amikacin, tobramycin,
cefoxitin, clarithromycin, doxycycline, sulfamethoxazole and imipenem.
- Cooksey RC, de Waard JH, Yakrus MA, Rivera I, Chopite M, Toney SR, Morlock GP, Butler WR. Mycobacterium cosmeticum sp.
nov., a novel rapidly growing species isolated from a cosmetic infection and from a nail salon. Int J Syst Evol Microbiol 2004; 54:
- John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
- Cooksey RC, de Waard JH, Yakrus MA, et al. Mycobacterium cosmeticum, Ohio and Venezuela. Emerg Infect Dis. 2007;13(8):
Positive results for arylsulfatase (14 days), iron uptake, and nitrate reduction.
Can utilize as sole carbon source L-arabinose, citrate, i-myo-inositol, D-mannitol and xylose.
Negative results for arylsulfatase (3 days) and niacin production.
No utilization of sorbitol as sole carbon source.
(c) Costin Stoica