Mycobacterium conceptionense
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Taxonomy
Morphology
Cultural characteristics
Biochemical characters
Ecology
Pathogenicity
References
Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium conceptionense Adekambi et al. 2006.
Member of the Mycobacterium fortuitum complex.
Acid-fast rods. Gram-positive.
Colonies are nonpigmented and appear on 5% sheep blood agar, Middlebrook
7H10 agar, and egg-based Lowenstein-Jensen slants in 2 to 5 days at temperatures
between 25 and 37 ºC, optimally at 30 ºC. No growth occurs at 42 ºC. Grows in the
presence of 5% (w/v) NaCl.
Isolated from wound liquid outflow, bone tissue biopsy, excised skin tissue, subcutaneous abscess and sputum.
Susceptible in vitro to imipenem, minocycline, doxycycline, clarithromycin, erythromycin, azithromycin, amikacin, ciprofloxacin,
ofloxacin, sparfloxacin, and amoxicillin clavulanate. Resistant to penicillin, rifampin, amoxicillin, and vancomycin.
Associated with posttraumatic osteitis. May cause pulmonary and skin infections, and prostetic infections.
- Adekambi T, Stein A, Carvajal J, Raoult D, Drancourt M. Description of Mycobacterium conceptionense sp. nov., a Mycobacterium
fortuitum group organism isolated from a posttraumatic osteitis inflammation. J Clin Microbiol 2006; 44:1268-1273.
- John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
- Kim SY, Kim MS, Chang HE, et al. Pulmonary infection caused by Mycobacterium conceptionense. Emerg Infect Dis. 2012;18(1):
174-176. doi:10.3201/eid1801.110251.
- Liao CH, Lai CC, Huang YT, Chou CH, Hsu HL, Hsueh PR. Subcutaneous abscess caused by Mycobacterium conceptionense in
an immunocompetent patient. J Infect. 2009;58:308–9. doi:10.1016/j. jinf.2009.02.012.
- Thibeaut S, Levy PY, Pelletier ML, Drancourt M. Mycobacterium conceptionense infection after breast implant surgery, France.
Emerg Infect Dis. 2010.
- Keun Hwa Lee, Sang Taek Heo, Sung-Wook Choi, Da Hee Park, Young Ree Kim, Seung Jin Yoo. Three Cases of Postoperative
Septic Arthritis Caused by Mycobacterium conceptionense in the Shoulder Joints of Immunocompetent Patients. Journal of
Clinical Microbiology Feb 2014, 52 (3) 1013-1015; DOI: 10.1128/JCM.02652-13
- Lamy B, Marchandin H, Hamitouche K, Laurent F. Mycobacterium setense sp. nov., a Mycobacterium fortuitum-group organism
isolated from a patient with soft tissue infection and osteitis. Int J Syst Evol Microbiol 2008; 58:486-490.
Positive results for arylsulfatase (3 days), alkaline phosphatase, catalase, alpha-glucosidase, nitrate reduction, penicillinase,
pyrazimidase, iron uptake, and acetoin production.
Can utilize inositol as sole carbon source.
Negative results for arginine dihydrolase, gelatinase, beta-glucuronidase, beta-galactosidase, indole production, lysine
decarboxylase, niacin accumulation, ornithine decarboxylase, pyrrolidonyl arylamidase, and urease.
No utilization as sole carbon source of D-glucose, D-mannitol, sorbitol, rhamnose, D-saccharose, D-melobiose, amygdalin,
L-arabinose or citrate.
(c) Costin Stoica