Phylum Actinobacteria, Class Actinobacteria, Order Actinomycetales, Suborder Corynebacterineae, Family Mycobacteriaceae, Genus
Mycobacterium, Mycobacterium branderi Koukila-Kahkola et al. 1995.
Acid-fast, rods, delicate, slender, and often slightly curved (1.2-3.0 μm in length).
Colonies are smooth, often umbonate, non-chromogenic, and off-white to grayish
in color. Growth occurs on Middlebrook 7H11 agar after incubation for 2-3 weeks.
Temperature range for growth is 25-45 ºC.
Isolated from from nine patients, some of whom had cavitary mycobacteriosis of the lungs. Susceptible to ethambutol (2 μg/ml),
streptomycin (8 μg/ml), ethionamide, and capreomycin. Resistant to isoniazid (1 μg/ml), rifampin (32 μg/ml), and cycloserine.
Considered as a potential human pathogen.
- John G. Magee and Alan C. Ward 2012. Family III. Mycobacteriaceae Chester 1897, 63AL in Bergey’s Manual of Systematic
Bacteriology, Volume Five The Actinobacteria, Part A, Michael Goodfellow & al. (editors), 312-375.
- Koukila-Kahkola P, Springer B, Bottger EC, Paulin L, Jantzen E, Katila ML. Mycobacterium branderi sp. nov., a new potential
human pathogen. Int J Syst Bacteriol 1995; 45:549-553.
- Okazaki M, Ohkusu K, Hata H, Ohnishi H, Sugahara K, Kawamura C, Fujiwara N, Matsumoto S, Nishiuchi Y, Toyoda K, et al.
Mycobacterium kyorinense sp. nov., a novel, slow-growing species, related to Mycobacterium celatum, isolated from human
clinical specimens. Int J Syst Evol Microbiol 2009; 59:1336-1341.
Positive results for arylsulfatase (14 days), nicotinamidase (weak reaction) and
pyrazinamidase (weak reaction).
Negative results for arylsulfatase (3 days), Heat-stable catalase (68 ºC), semiquantitative catalase test, niacin accumulation, nitrate
reduction, Tween 80 hydrolysis, and urease.
(c) Costin Stoica