Phylum Proteobacteria, Class Epsilonproteobacteria, Order Campylobacterales, Family Helicobacteraceae, Genus Helicobacter,
Helicobacter typhlonius Franklin, Gorelick, Riley, Dewhirst, Livingston, Ward, Beckwith and Fox 2002.
Synonym: Helicobacter typhlonicus Franklin et al. 1999.
Filamentous spiral or curved rods, 0.3 x 2-5 μm. Motile by means of single bipolar
sheathed flagella. Nonspore-forming.
Culture on 5% sheep blood agar under microaerobic conditions results in pinpoint
colonies. No anaerobic or aerobic growth. Weak growth on media containing 1.0%
glycine. No growth in the presence of 1.5% NaCl. Grow at 37 and 42 ºC; not at 25 ºC.
Isolated from feces and ceca of laboratory mice.
Sensitive to nalidixic acid (30 μg disk diffusion tests), but resistant to cephalothin (30 μg).
May cause typhlocolitis, hepatitis, and inflammatory bowel disease in immunodeficient mice, but can also be recovered from normal
- George M. Garrity, Julia A. Bell and Timothy Lilburn, 2001. Family II. Helicobacteraceae. In: Bergey’s Manual of Systematic
Bacteriology, Second edition, Vol 2, part C, George M. Garrity (Editor-in-Chief), pp 1168-1195.
- Craig L. Franklin, Peter L. Gorelick, Lela K. Riley, Floyd E. Dewhirst, Robert S. Livingston, Jerrold M. Ward, Catherine S. Beckwith,
and James G. Fox. Helicobacter typhlonius sp. nov., a Novel Murine Urease-Negative Helicobacter Species. J. Clin. Microbiol.
November 2001 39:11 3920-3926.
Positive results for catalase, nitrate reduction, and oxidase.
Negative results for urease, H2S production, indoxyl-acetate hydrolysis, alkaline phosphatase, gamma-glutamyltransferase, and
(c) Costin Stoica