Phylum Actinobacteria, Class Actinobacteria, Subclass Actibacteridae, Order Actynomycetales, Suborder Corynebacterinae, Family
Corynebacteriaceae, Genus Corynebacterium, Corynebacterium minutissimum (Sarkany et al. 1962) Collins and Jones 1983.
Two biotipes were described.
Historical synonyms: Corynebacterium minutissimum Sarkany et al. 1962.
Typical diphtheroids with single cells, V forms, palisades and clustering as “Chinese
Colonies are convex, with shiny and moist surface, have entire edges and 1.0-1.5
mm in diameter after 1 day of incubation; coral-red to orange fluorescence under
Wood’s light (365 nm) on rich media (containing 20% fetal calf serum). Most colonies
are of a creamy texture, but some may also be sticky.
CAMP test is negative. Facultatively anaerobic. Can grow in 6.5% NaCl.
Habitat is the human skin; is a member of the normal human skin flora. Susceptible to O/129.
Implicated in erythrasma, an asymptomatic skin infection and probably a polymicrobial process in human.
Deep tissue invasion in a patient with recurrent breast abscesses.
Probably cases of bacteremia and one case of postoperative neck abscess in human.
Other disease association: wound infections, urinary tract infections.
- Funke G., von Graevenitz A., Clarridge III J.E., and Bernard K.A., 1997. Clinical Microbiology of Coryneform Bacteria. Clinical
Microbiology Rewiews Vol. 10, No. 1, p. 125-159.
- Funke G., 2006. Corynebacteria and rare coryneforms. In: Topley & Wilson’s Microbiology & Microbial Infections, 10th Edition,
Edited by Borriello S.P., Murray P.R. and Funke G.,Edward Arnold (Publishers) Ltd., Bacteriology, volume 2.
- Cummins C.S., Lelliott R.A. and Rogosa M., 1975. Genus Corynebacterium Lehmann and Neumann 1896 . In: Buchanan R.E.
and Gibbons N.E. (Editors), Bergey’s Manual of Determinative Bacteriology, Eight Edition, The Williams & Wilkins Company,
- Diaconescu A. si Damian M., 2009. Identificarea corinebacteriilor. In: Buiuc D., Negut M. (Editori), Tratat de Microbiologie Clinica,
Editia a III-a, Editura Medicala, Bucuresti, 620-651.
- Holt J.G., Krieg N.R., Sneath P.H.A., Staley J.T. and Williams S.T., 1994. Bergey's Manual of Determinative Bacteriology, Ninth
Edition, Williams & Wilkins, A Waverly Company, Baltimore, pp 571-596.
Fermentative metabolism. Biotype1 ferments sucrose, while biotype 2 doesn't.
Positive results for alkaline phosphatase, DNase, hippurate hydrolysis, pyrazinamidase, tyrosine hydrolysis, acid production from:
fructose, glucose, maltose & ribose.
Negative results for casein hydrolysis, catalase, esculin hydrolysis, gelatinase, beta-glucuronidase, beta-galactosidase,
alpha-glucosidase, lipophilism, methyl red, nitrate reduction, pyrrolidonyl arylamidase, urease, acid production from: glycogen,
lactose, raffinose, starch, trehalose & xylose.
Acid production from mannitol is variable.
(c) Costin Stoica