Phylum Actinobacteria, Class Actinobacteria , Subclass Actibacteridae, Order Actynomycetales, Suborder Corynebacterinae, Family
Corynebacteriaceae, Genus Corynebacterium, Corynebacterium falsenii Sjoden, Funke, Izquierdo, Akervall and Collins 1998.
Historical synonyms: EF (EnevoldFalsen) group 42 bacteria.
Gram-positive typically club-shaped rods which appear as single cells, in pairs or in
small clusters. Nonmotile. Nonspore-forming.
On Columbia agar plates (Difco) supplemented with 5% sheep blood at 37 ºC in a
5% CO2 atmosphere the colonies are whitish, circular with entire edges, convex,
glistening, up to 2 mm in diameter after 24 h incubation, of creamy consistency, and
start to develop a yellowish pigment after 72 h incubation. Weak anaerobic growth.
Isolated from sterile body fluids (blood, cerebrospinal fluid).
Susceptible to cephalotin, ciprofloxacin, gentamicin, erythromycin, imipenem, rifampicin, tetracycline and vancomycin.
- Sjoden B., Funke G., Izquierdo A., Akervall E. and Collins M.D.,1998. Description of some coryneform bacteria isolated from
human clinical specimens as Corynebacterium falsenii sp. nov. IJSB 48, 69-74.
- Funke G ., 2006. Corynebacteria and rare coryneforms. In: Topley & Wilson’s Microbiology & Microbial Infections, 10th Edition,
Edited by Borriello S.P., Murray P.R. and Funke G., Edward Arnold (Publishers) Ltd., Bacteriology, volume 2.
Fermentative metabolism. Non-partially-acid-fast.
Description of most biochemical tests is based on API CORYNE and API CH.
Positive results for alkaline phosphatase, acid phosphatase, catalase, esterase (C4), esterase lipase (C8), pyrazinamidase (weak
reaction), urease (weak reaction), acid production from: 5-ketogluconate, galactose, glycerol, glucose (weak reaction), ribose &
Negative results for casein hydrolysis, esculin hydrolysis, beta-glucuronidase, beta-galactosidase, alpha-glucosidase, lipophilism,
nitrate reduction, tyrosine hydrolysis, acid production from: N-acetylglucosamine, adonitol, amygdalin,arabinose, arabitol, arbutin,
cellobiose, dulcitol, erythritol, fucose, beta-gentiobiose, 2-ketogluconate, gluconate, glycogen, inositol, inulin, lyxose, mannitol,
melibiose, melezitose, raffinose, salicin, sorbose, sorbitol, sucrose, turanose, xylitol & xylose.
Variable results for acid production from: fructose, lactose, maltose, rhamnose & tagatose.
(c) Costin Stoica