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Phylum Actinobacteria, Class Actinobacteria, Subclass Actibacteridae, Order Actynomycetales, Suborder Corynebacterinae, Family
Corynebacteriaceae, Genus Corynebacterium,
Corynebacterium durum Riegel, Heller, Prevost, Jehl and Monteil 1997.
Gram-positive long, pleomorphic rods (3 to 4 µm long) or occasionally filaments (15
to 30 µm long) with swollen ends. Nonmotile. Nonspore-forming.
After 48-72 h of incubation on blood agar plates in an aerobic atmosphere at 37 ºC,
cultures appeared as small (up to 1 mm), convoluted, convex, rough, raised beige
colonies with irregular edges and no hemolytic activity. Strong adherence to the
medium occurred; in an aerobic atmosphere supplemented with 10% CO
2, exhibited
larger colonies with a dense center, nearly regular margins and slightly adherent to
agar. Weak anaerobic growth.
In liquid media, the organisms produce a sediment, leading to a granular
appearance of the culture after the broth was shaken.
Isolated from respiratory tract specimens of human patients with a history of pneumonia.
Susceptible to ampicillin, amoxicillin-clavulanic acid, piperacillin, cefotaxime, gentamicin, ciprofloxacin, minocycline, erythromycin,
rifampin, teicoplanin, and vancomycin.
Undetermined.
  1. Riegel P., Heller R., Prevost G., Jehl F. and Monteil H. 1997. Corynebacterium durum sp. nov., from human clinical specimens.
    IJSB Vol. 47, No.4, 1107-1111.
  2. Funke G., 2006. Corynebacteria and rare coryneforms. In: Topley & Wilson’s Microbiology & Microbial Infections, 10th Edition,
    Edited by Borriello S.P., Murray P.R. and Funke G., Edward Arnold (Publishers) Ltd., Bacteriology, volume 2.
Fermentative metabolism. Non-partially-acid-fast.
Description of most biochemical test is based on API CORYNE.

Positive results for nitrate reduction, pyrazinamidase, acid production from: fructose, galactose, glucose, maltose, mannitol & sucrose.

Negative results for alkaline phosphatase, alpha-glucosidase, beta-galactosidase, beta-glucuronidase, gelatin hydrolysis,
lipophilism, tyrosine hydrolysis, acid production from: lactose, ribose, trehalose & xylose.

Weak and variable results for esculin hydrolysis & urease.
Corynebacterium durum
(c) Costin Stoica
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