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Phylum Actinobacteria, Class Actinobacteria , Subclass Actibacteridae, Order Actynomycetales, Suborder Corynebacterinae, Family
Corynebacteriaceae, Genus Corynebacterium,
Corynebacterium amycolatum Collins, Burton and Jones, 1988.

Historical synonyms: CDC coryneform groups F-2 and I-2.
Pleomorphic coryneform rods with single cells, V forms or "Chinese letters".
Very typically dry, waxy and grayish white with irregular edges colonies, 1.0-1.5 mm in
diameter after 24 hours of incubation at 37 ºC. CAMP test is negative.
Isolated from swabs of the skin of healthy people.
Mostly O/129 resistant. May be multiresistant to beta-lactams, macrolides, clindamycin, aminoglycosides, ciprofloxacin, and rifampin.
Susceptible to glycopeptides and, majority strains to tetracycline.
A postoperative sternal wound infection, a case of peritonitis associated with a continuous ambulatory peritoneal dialysis and other
opportunistic infections, foreign body infections, bacteremia, urinary tract infections.
  1. Funke G., von Graevenitz A., Clarridge III J.E., and Bernard K.A., 1997. Clinical Microbiology of Coryneform Bacteria. Clinical
    Microbiology Rewiews Vol. 10, No. 1, p. 125-159.
  2. Funke G ., 2006.Corynebacteria and rare coryneforms. In: Topley & Wilson’s Microbiology & Microbial Infections, 10th Edition,
    Edited by Borriello S.P., Murray P.R. and Funke G.,Edward Arnold (Publishers) Ltd., Bacteriology, volume 2.
  3. Holt J.G., Krieg N.R., Sneath P.H.A., Staley J.T. and Williams S.T., 1994. Bergey's Manual of Determinative Bacteriology, Ninth
    Edition, Williams & Wilkins, A Waverly Company, Baltimore, pp 571-596.
Fermentative metabolism. Non-partially-acid-fast.

Positive results for alkaline phosphatase, methyl red, pyrazinamidase, acid production
from: fructose, glucose & mannose.

Negative results for casein hydrolysis, esculin hydrolysis, mycolic acids, lipophilism, tyrosine hydrolysis, acid production from:
arabinose, galactose, lactose, mannitol, raffinose, rhamnose, salicin, starch & xylose.


Variable results for hippurate hydrolysis, nitrate reduction, urease, acid production from: maltose, sucrose & trehalose.
Corynebacterium amycolatum
(c) Costin Stoica
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