Phylum Firmicutes, Class Clostridia, Order Clostridiales, Family Clostridiaceae, Genus Clostridium, Cluster I (Clostridium sensu
stricto), Clostridium cadaveris (Klein 1899) McClung and McCoy 1957.
Historical synonym: Bacillus cadaveris Klein 1899, Plectridium cadaveris (Klein) Prevot 1938.
Gram-positive, straight rods, 0.5-1.3 x 1.4-9.4 µm, occuring singly or in pairs. Motile by
peritrichous flagella (variable). Spores are oval, terminal, and swelling the cell.
Sporulation of most strains occurs most readily on chopped-meat agar slants
incubated at 30 ºC for 1 week.
Surface colonies on blood agar plates are 0.5–3 mm in diameter, circular, convex,
translucent to opaque, smooth, shiny, entire to slightly scalloped. Hemolysis is
variable. Cultures in PYG broth are turbid with a smooth sediment and have a pH of
4.9–5.4 after incubation for 5 days. Slight growth in nutrient broth; profuse growth with
heavy sediment in glucose broth. Grow at 25 -45 ºC, optimum 30-37 ºC. Growth is
inhibited in 6.5% NaCl; most strains are inhibited by 20% bile.
Growth is stimulated by fermentable carbohydrates. Abundant gas is detected in PYG
deep agar cultures. Major products of metabolism in PYG broth: acetic and butyric
acids, abundant H2, ethyl and butyl alcohols.
Isolated from soil, marine sediment, animal and human feces, snake venom, human clinical specimens from abscesses, wounds,
and blood. Susceptible to penicillin G.
Non-pathogenic for laboratory animals. Toxin is not produced.
Isolated from human clinical specimens from abscesses, wounds, and blood.
- N.A. Logan and P. De Vos, 2009. Genus I. Clostridium Prazmowski 1880. In: (Eds.) P.D. Vos, G. Garrity, D. Jones, N.R. Krieg, W.
Ludwig, F.A. Rainey, K.-H. Schleifer, W.B. Whitman. Bergey’s Manual of Systematic Bacteriology, Volume 3: The Firmicutes,
- Smith L.D.S. and Hobbs G., 1975. Genus III. Clostridium Prazmowski 1880. In: (Eds.) Buchanan R.E. and Gibbons N.E., Bergey’s
Manual of Determinative Bacteriology, Eighth Edition , The Williams & Wilkins Company, Baltimore, 551-572.
- Secasiu V., 2001. Boli produse de germeni din genul Clostridium. In: Boli infectioase ale animalelor, Moga Manzat R., Ed.
Brumar, Timisoara, 481-612.
H2 is produced in large amounts. Milk reaction is weak. Meat digestion is positive.
Positive results for ammonia production, casein hydrolysis, DNase, H2S production, indole production, neutral red reduction,
substrate utilized and/or acid produced from glucose.
Negative results for esculin hydrolysis, lecithinase, lipase, nitrate reduction, starch hydrolysis, substrate utilized and/or acid produced
from: amygdalin, arabinose, cellobiose, dulcitol, galactose, glycogen, inositol, inulin, lactose, maltose, mannitol, melezitose,
melibiose, raffinose, rhamnose, ribose, salicin, sorbitol, sorbose, starch, sucrose, trehalose & xylose.
Variable results for hydrolysis of hippurate, resazurin reduction, substrate utilized and/or acid produced from: fructose & mannose
(c) Costin Stoica